Examples of its interventions could range from medical therapeutics, supplementation, and guidance for lifestyle change.
Chi Longevity will also introduce gut health, physical performance assessment, and sleep and stress optimisation programmes. These services will be available in both the hotel and in its existing clinic.
Age-related concerns
Chi Longevity’s focus on cellular ageing targets oxidative stress and inflammation using advanced nutraceuticals like NAD+ precursors and CoQ10. Bespoke plans are crafted based on biomarkers, ensuring personalised care.
“We cannot stress the importance of a customised approach. Often, we see clients listening to general advice on social media, for example the need to take supplements. A generalised approach often never works and can even be detrimental to health,” said Cooper.
For example, popular supplements targeting biological ageing, like NMN and Urolithin A, are gaining attention in this space. However, the clinic emphasises the importance of verifying the quality of such products.
A recent NUS Medicine study led by Professor Maier highlighted discrepancies between actual and labelled amount of anti-ageing ingredients in supplements.
Therefore, the clinic takes a disciplined and bespoke approach to supplementation, testing each client’s baseline health markers before recommending any supplements.
“We’ve developed packages that cater to this need, combining advanced assessments such as epigenetic, microbiome, and cognitive assessments with ongoing intervention support in nutrition, fitness, and mental health,” said Cooper.
Moreover, there is a rising demand for tech-enabled health monitoring, which the clinic will incorporate through continuous glucose monitoring (CGM), sleep tracking, and wearable fitness technology.
This will allow clients to take control of their health in real time while the Chi Longevity team provides personalised intervention plans based on the data gathered.
The clinic focusses on markers that reveal subtle imbalances before they manifest as disease.
Using advanced assessments like DNA methylation testing and cardiovascular profiling, Chi Longevity tailors interventions to prevent metabolic disorders and promote long-term health.
The clinic also does continuous glucose monitoring, providing insights into blood sugar control and insulin sensitivity to manage metabolic syndrome.
“These biomarkers allow us to predict future health trends, intervene early, and customise interventions such as dietary changes, nutraceuticals, or lifestyle modifications,” said Dr Oh Eu Leong, resident physician at Chi Longevity.
Prevailing health concerns
Some common concerns include sleep disturbances and gut health. The clinic employs a range of evidence-based supplements targeted to specific health concerns. Every recommendation is guided by biomarker trends, ensuring precise, targeted interventions for optimal outcomes, said Dr Oh.
For example, melatonin is prescribed for circadian rhythm alignment, glycine to improve subjective sleep quality and reduce fatigue in sleep-restricted individuals. L-theanine is another supplement that promotes relaxation without sedation, potentially improving sleep quality.
As for supporting gut health, a tailored combination of prebiotics and probiotics could be prescribed to improve gut microbiome diversity and composition.
“Our recommendations are personalised and data-driven. For example, high oxidative stress or inflammation markers may warrant supplements such as CoQ10, glutathione, or alpha-lipoic acid. Nutrient deficiencies like low magnesium, zinc, or vitamin D levels are common, and correcting these can improve metabolic and immune function.
“As for managing metabolic dysfunction, elevated fasting insulin or HbA1c, for example, might prompt the use of medication or fibre supplements to enhance insulin sensitivity,” said Dr Oh.
To monitor the effectiveness of interventions, the clinic assesses progress through periodic re-testing of key biomarkers every three to six months. It also uses wearable technology and continuous glucose monitoring to assess real-time changes in metrics like heart rate, deep sleep, and glucose levels.
If a client’s biomarkers do not improve as expected, adjustments are made accordingly to ensure ongoing progress toward health goals, said Dr Oh.
Growing appeal of luxury wellness in Asia
Luxury wellness is reshaping hospitality, appealing to discerning clients from jet-setting executives to families focused on longevity, said Cooper.
“Chronological age is the single most significant risk factor for a range of chronic diseases and cellular degradation. Everyone ages, so in theory everyone can benefit from health optimisation services.
“Broadly speaking, our clients are looking to feel great now and feel great 20–30 years down the line. We’ve seen clients in their 20s and in their 80s, but the majority of our clients are between 45–65,” said Cooper.
There is also an increasing number of clients in their late 30s and early 40s, who are starting a family and want to make sure they remain healthy to see their kids grow up.
This collaboration is part of the clinic’s strategy and vision of providing evidence-based medical services to a discerning clientele. The aim is to create a new model of luxury medical care, and to help a wider audience – in and beyond Singapore – live longer, healthier lives, said Cooper.
This aligns with the hotel’s service expansion, which reflects the expectations of global travellers, who are driven by the desire for holistic health and rejuvenation.
“Particularly in this region, we are seeing wellness woven into every aspect of daily life and this demand is playing a key role in tourism and hospitality.
“Whether it be for city hotels catering to business leisure guests’ focus on mental health and well-being, or connecting with the younger generation of Gen Zers and millennials who are seeking wellness solutions in their overall lifestyles, we recognise the unique needs and preferences of these guests and have tailored our services to cater to their expectations,” said Peter Draminsky, regional vice president and general manager of Four Seasons Hotel Singapore.
